Error TIMEOUT WAITING FOR ACK - RabbitMq Publiser Confirms Async Implementation - asynchronous

Question

We have implemented publisher confirms asynchronously i.e. we have setup callbacks on RabbitTemplates to get response from RabbitMq; but we are getting below exception in the logs:-
{"ts":"02 24 2021 14:33:21.308","th":"connectionFactory4002","tenant":"","user":"null","trxid":"","level":"DEBUG","logger":"org.springframework.amqp.rabbit.connection.PublisherCallbackChannelImpl","msg":Sending confirm PendingConfirm [correlationData=CorrelationData [id=7d329ab2-2472-4222-91d0-9bc68dc405c7] cause=clean channel shutdown; protocol method: #method<channel.close>(reply-code=406, reply-text=TIMEOUT WAITING FOR ACK, class-id=0, method-id=0)] }
"ERROR","logger":"com.rabbitmq.client.impl.ChannelN","msg":{​​​​​[com.rabbitmq.client.impl.ChannelN.waitForConfirmsOrDie(ChannelN.java:254),org.springframework.amqp.rabbit.connection.PublisherCallbackChannelImpl.waitForConfirmsOrDie(PublisherCallbackChannelImpl.java:676),org.springframework.amqp.rabbit.connection.CachingConnectionFactory$CachedChannelInvocationHandler.lambda$asyncClose$1(CachingConnectionFactory.java:1371),java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1142),java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:617),java.lang.Thread.run(Thread.java:745)]}​​​​​ ,"ERR": {​​​​​ java.util.concurrent.TimeoutException
at com.rabbitmq.client.impl.ChannelN.waitForConfirms(ChannelN.java:223)
at com.rabbitmq.client.impl.ChannelN.waitForConfirmsOrDie(ChannelN.java:249)
at org.springframework.amqp.rabbit.connection.PublisherCallbackChannelImpl.waitForConfirmsOrDie(PublisherCallbackChannelImpl.java:676)
at org.springframework.amqp.rabbit.connection.CachingConnectionFactory$CachedChannelInvocationHandler.lambda$asyncClose$1(CachingConnectionFactory.java:1371)
at java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1142)
at java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:617)
at java.lang.Thread.run(Thread.java:745)
--Connection Factory Config
<bean id="connectionFactory"
class="org.springframework.amqp.rabbit.connection.CachingConnectionFactory">
<constructor-arg value="#{messagingProperties['mq.hostname']}" />
<property name="virtualHost" value="#{messagingProperties['mq.virtual-host']}" />
<property name="username" value="#{messagingProperties['mq.username']}" />
<property name="password" value="#{messagingProperties['mq.password']}" />
<property name="connectionTimeout" value="10000"/>
<property name="channelRpcTimeout" value="60000"/>
<property name="channelCacheSize" value="25" />
</bean>
We have following queries regarding this :
How to prevent this error/log?
Is there message loss due to the above error?
Apart from resource utilization, is there any side impact of this error?
Do the confirmCallBack/returnCallBack call this method(waitForConfirmsOrDie) behind the scenes?