add random missingness and random noise in a dataframe - r

I have a dataframe, I want to add some random missingness in the data and add random noise
22RV1 23132-87 639-V
exp_TSPAN6 7.951917 3.524705 12.04370
exp_TNMD 8.079243 3.580134 12.20077
exp_DPM1 8.509788 6.853905 4.406769
exp_SCYL3 7.642608 7.613985 8.741316
exp_C1orf112 3.231196 7.695874 10.668163
Desired Output
22RV1 23132-87 639-V
exp_TSPAN6 7.951917 2.524705 12.04370
exp_TNMD 7.079243 Nan 13.20077
exp_DPM1 8.509788 6.853905 4.406769
exp_SCYL3 Nan 6.613985 Nan
exp_C1orf112 3.231196 7.695874 9.668163
I tried this function but its too slow for dataset with 1000 columns and 500 rows. is there an efficient way to add both randomness and noise?
insertNA <- function(df,NAratio) {
sel <- sample( nrow(df)*ncol(df), size = NAratio*nrow(df)*ncol(df) )
for (i in c(1:length(sel))) {
a <- as.integer((sel[i]-1)/ncol(df)+1)
b <- sel[i] - (a-1)*ncol(df)
df[a,b] <- NA
}
return(df)
}

Although you want to add noise and missingness randomly there should still be some rules defined.
To add noise I use rnorm function and I change 20% of the values to NA here. You can change the conditions based on your requirement.
n <- nrow(df)
df[] <- lapply(df, function(x) x + rnorm(n) *
sample(c(1, NA),n, replace = TRUE, prob = c(0.8, 0.2)))
df
# X22RV1 X23132.87 X639.V
#exp_TSPAN6 7.172716 5.179046 10.417945
#exp_TNMD 7.568185 3.794910 11.130833
#exp_DPM1 7.701909 6.799382 3.003337
#exp_SCYL3 8.034432 NA 8.510112
#exp_C1orf112 NA NA 10.981735

Related

How to loop and use if else on this example with logical expressions using R

I have two lengthy data sets with several columns and different lengths, for this example lets subset to few rows and just 3 columns:
Temp <- c(12.9423 ,12.9446 ,12.9412 ,12.9617 ,12.9742 ,12.9652 ,12.9463, 12.9847 ,12.9778,
12.9589, 12.9305, 12.9275 ,12.8569 ,12.8531 ,12.9092, 12.9471, 12.9298, 12.9266,
12.9374 ,12.9385, 12.9505, 12.9510, 12.9632 ,12.9621 ,12.9571, 12.9492 ,12.8988,
12.8895 ,12.8777, 12.8956, 12.8748 ,12.7850 ,12.7323, 12.7546 ,12.7375 ,12.7020,
12.7172, 12.7015, 12.6960, 12.6944, 12.6963, 12.6928, 12.6930 ,12.6883 ,12.6913)
Density <- c(26.38635 ,26.38531 ,26.38429, 26.38336, 26.38268 ,26.38242, 26.38265, 26.38343,
26.38486, 26.38697 ,26.38945, 26.39188, 26.39365, 26.39424 ,26.39376 ,26.39250,
26.39084 ,26.38912 ,26.38744 ,26.38587, 26.38456 ,26.38367, 26.38341 ,26.38398,
26.38547 ,26.38793 ,26.39120 ,26.39509, 26.39955 ,26.40455, 26.41002, 26.41578,
26.42126, 26.42593 ,26.42968, 26.43255 ,26.43463, 26.43603 ,26.43693 ,26.43750,
26.43787, 26.43815, 26.43841 ,26.43871 ,26.43904)
po4 <- c(0.4239840 ,0.4351156, 0.4456128, 0.4542392, 0.4608510, 0.4656445, 0.4690847,
0.4717291, 0.4742391 ,0.4774904 ,0.4831152, 0.4922122, 0.5029904, 0.5128720,
0.5190209, 0.5191368 ,0.5133212, 0.5027542 ,0.4905301 ,0.4796467 ,0.4708035,
0.4638879, 0.4578364 ,0.4519745, 0.4481336, 0.4483697, 0.4531310, 0.4622930,
0.4750474 ,0.4905152 ,0.5082183 ,0.5278212 ,0.5491580 ,0.5720519, 0.5961127,
0.6207716 ,0.6449603, 0.6675704 ,0.6878331 ,0.7051851,0.7195461, 0.7305200,
0.7359634 ,0.7343541, 0.7283988)
PP14 <- data.frame(Temp,Density,po4) ##df1
temp <- c(13.13875, 13.13477 ,13.12337 ,13.10662 ,13.09798 ,13.09542 ,13.08734 ,13.07616,
13.06671 ,13.05899, 13.05890 ,13.05293 ,13.03322, 13.01515, 13.02552 ,13.01668,
12.99829, 12.97075 ,12.95572 ,12.95045 ,12.94541 ,12.94365 ,12.94609 ,12.94256,
12.93565 ,12.93258 ,12.93489 ,12.93209 ,12.92219 ,12.90730 ,12.90416 ,12.89974,
12.89749 ,12.89626 ,12.89395, 12.89315 ,12.89274, 12.89276 ,12.89293 ,12.89302)
density <- c( 26.35897, 26.36274 ,26.36173 ,26.36401 ,26.36507 ,26.36662 ,26.36838,
26.36996,
26.37286 ,26.37452 ,26.37402, 26.37571 ,26.37776, 26.38008 ,26.37959 ,26.38178,
26.38642 ,26.39158 ,26.39350, 26.39467, 26.39601, 26.39601, 26.39596 ,26.39517,
26.39728 ,26.39766, 26.39774, 26.39699 ,26.40081 ,26.40328 ,26.40416, 26.40486,
26.40513 ,26.40474 ,26.40552 ,26.40584, 26.40613, 26.40602 ,26.40595 ,26.40498)
krho <- c( -9.999999e+06, -1.786843e+00, -9.142976e-01, -9.650734e-01, -2.532397e+00,
-3.760537e+00, -2.622484e+00, -1.776506e+00, -2.028391e+00, -2.225910e+00,
-3.486826e+00, -2.062341e-01, -3.010643e+00, -3.878437e+00, -3.796426e+00,
-3.227138e+00, -3.335446e+00, -3.738037e+00, -4.577778e+00, -3.818099e+00,
-3.891467e+00, -4.585045e+00 ,-3.150283e+00 ,-4.371089e+00 ,-3.902601e+00,
-4.546019e+00, -3.932538e+00, -4.331247e+00, -4.508137e+00, -4.789201e+00,
-4.383820e+00, -4.423486e+00, -4.334641e+00, -4.330544e+00, -4.838604e+00,
-4.729123e+00, -4.381797e+00, -4.207365e+00, -4.276804e+00, -4.001305e+00)
MS14 <- data.frame(temp,density,krho) ##df2
So now I would like to loop through both data sets and check if MS14$density=PP14$Density if it is true then I would like to use the column krho in that row to multiply it by delta po4 that corresponds to the same density so diff(po4) in that row or range. something like
#MS14$krho[i] * diff(PP14$po4)[i]
BUT when I run
PP14$Density == MS14$density
of course it is always FALSE, because the large decimal numbers, none is exactly the same. I solved that by round the numbers to the 3rd decimal, but it should be a way to include that in the code so density +- 0.005 for example. Well or just rounding it to the 3rd decimal like:
PP14$Density_round2 <- round(PP14$Density ,digit=2)
In any case I am not sure if I should use a nested loop to check both columns and make the operations accordingly or if it would be better to create a new data.frame with the intersect of each data.frame:
common <- intersect(PP14$Density, MS14$density)
and then make calculations....(??)
So I would probably need a nested loop like:
{for i:PP14
for j:MS14
new-> PP14$Density[i] == MS14$density[j]
#if new is true then PP14$krho[i]* MS14$diff(po4)[j]#[for that particular row]
#and print it into a new data.frame df3
#}
So please, feel free to suggest the best way to proceed.. there might be several ways to do it..
Thank you so much in advance!!
Ps: suggestions using Matlab are also welcome
Something like this?
compareDec <- function(x, y, digits = NULL, tol = .Machine$double.eps^0.5){
if(is.null(digits)){
abs(x - y) < tol
} else {
round(x, digits = digits) == round(y, digits = digits)
}
}
icomp <- outer(MS14$density, PP14$Density, compareDec, digits = 2)
m <- outer(MS14$krho, c(0, diff(PP14$po4)))
new <- which(icomp, arr.ind = TRUE)
df3 <- cbind.data.frame(new, Prod = m[new])
head(df3)
# row col Prod
#1 17 1 0.00000000
#2 18 1 0.00000000
#3 19 1 0.00000000
#4 20 1 0.00000000
#5 17 2 -0.03712885
#6 18 2 -0.04161033

How to code the permutation equivalent of Mood's Median Test in R? (get the p values using permutation)

I can do it for the two sample t test but not for Median test or Wilcoxon test or Hodges Lehmann test
data_2000 <- c(500,450,600,700,550,551,552)
data_2019 <- c(560,460,620,720,540,600,750)
mean(data_2000)
mean(data_2019)
mean(data_2019) - mean(data_2000)
combined_data <- c(data_2000, data_2019)
set.seed(123)
null_dist <- c()
for (i in 1:100000) {
shuffled_data <- sample(combined_data)
shuffled_2000 <- shuffled_data[1:7]
shuffled_2019 <- shuffled_data[8:14]
null_dist[i] <- mean(shuffled_2019) - mean(shuffled_2000)
}
(p_value <- (sum(null_dist >= 49.57143) + sum(null_dist <=
`enter code here`-49.57143))/length(null_dist))
I think this is what you're trying to do. I altered your code as little as possible. There are packages like infer that will do this for you and the for loop is not the most efficient but it's plenty good enough and may help you learn. As long as we're looping I did mean and median at the same time since all other parts of the code are identical. ifelse is a nice easy way to make 1s and 0s to sum.
data_2000 <- c(500,450,600,700,550,551,552)
data_2019 <- c(560,460,620,720,540,600,750)
delta_mean <- mean(data_2019) - mean(data_2000)
delta_median <- median(data_2019) - median(data_2000)
combined_data <- c(data_2000, data_2019)
trials <- 100000
set.seed(123)
mean_diff <- c()
median_diff <- c()
for (i in 1:trials) {
shuffled_data <- sample(combined_data)
shuffled_2000 <- shuffled_data[1:7]
shuffled_2019 <- shuffled_data[8:14]
mean_diff[i] <- mean(shuffled_2019) - mean(shuffled_2000)
median_diff[i] <- median(shuffled_2019) - median(shuffled_2000)
}
p_mean <- sum(ifelse(mean_diff > delta_mean | mean_diff < -1 * delta_mean, 1, 0)) / trials
p_median <- sum(ifelse(median_diff > delta_median | median_diff < -1 * delta_median, 1, 0)) / trials
p_mean
#> [1] 0.31888
p_median
#> [1] 0.24446
Following up on your question about HL test. Quoting Wikipedia
The Hodges–Lehmann statistic also estimates the difference between two populations. For two sets of data with m and n observations, the set of two-element sets made of them is their Cartesian product, which contains m × n pairs of points (one from each set); each such pair defines one difference of values. The Hodges–Lehmann statistic is the median of the m × n differences.
You could run it on your data with the following code...
Do NOT run it 100,000 times the answer is the same everytime because you're already making all 49 possible pairings
hl_df <- expand.grid(data_2019, data_2000)
hl_df$pair_diffs <- hl_df$Var1 - hl_df$Var2
median(hl_df$pair_diffs)
[1] 49
You can do the Wilcoxon test with wilcox.test in the stats package (loaded by default as part of R core). You need to set exact = FALSE because an exact p-value is not possible if there are ties.
wilcox.test(data_2019, data_2000, exact = FALSE)
Wilcoxon rank sum test with continuity correction
data: data_2019 and data_2000
W = 33.5, p-value = 0.2769
alternative hypothesis: true location shift is not equal to 0
I'll update this when I figure out how to do the other tests.

cosine similarity(patient similarity metric) between 48k patients data with predictive variables

I have to calculate cosine similarity (patient similarity metric) in R between 48k patients data with some predictive variables. Here is the equation: PSM(P1,P2) = P1.P2/ ||P1|| ||P2||
where P1 and P2 are the predictor vectors corresponding to two different patients, where for example P1 index patient and P2 will be compared with index (P1) and finally pairwise patient similarity metric PSM(P1,P2) will be calculated.
This process will go on for all 48k patients.
I have added sample data-set for 300 patients in a .csv file. Please find the sample data-set here.https://1drv.ms/u/s!AhoddsPPvdj3hVTSbosv2KcPIx5a
First things first: You can find more rigorous treatments of cosine similarity at either of these posts:
Find cosine similarity between two arrays
Creating co-occurrence matrix
Now, you clearly have a mixture of data types in your input, at least
decimal
integer
categorical
I suspect that some of the integer values are Booleans or additional categoricals. Generally, it will be up to you to transform these into continuous numerical vectors if you want to use them as input into the similarity calculation. For example, what's the distance between admission types ELECTIVE and EMERGENCY? Is it a nominal or ordinal variable? I will only be modelling the columns that I trust to be numerical dependent variables.
Also, what have you done to ensure that some of your columns don't correlate with others? Using just a little awareness of data science and biomedical terminology, it seems likely that the following are all correlated:
diasbp_max, diasbp_min, meanbp_max, meanbp_min, sysbp_max and sysbp_min
I suggest going to a print shop and ordering a poster-size printout of psm_pairs.pdf. :-) Your eyes are better at detecting meaningful (but non-linear) dependencies between variable. Including multiple measurements of the same fundamental phenomenon may over-weight that phenomenon in your similarity calculation. Don't forget that you can derive variables like
diasbp_rage <- diasbp_max - diasbp_min
Now, I'm not especially good at linear algebra, so I'm importing a cosine similarity function form the lsa text analysis package. I'd love to see you write out the formula in your question as an R function. I would write it to compare one row to another, and use two nested apply loops to get all comparisons. Hopefully we'll get the same results!
After calculating the similarity, I try to find two different patients with the most dissimilar encounters.
Since you're working with a number of rows that's relatively large, you'll want to compare various algorithmic methodologies for efficiency. In addition, you could use SparkR/some other Hadoop solution on a cluster, or the parallel package on a single computer with multiple cores and lots of RAM. I have no idea whether the solution I provided is thread-safe.
Come to think of it, the transposition alone (as I implemented it) is likely to be computationally costly for a set of 1 million patient-encounters. Overall, (If I remember my computational complexity correctly) as the number of rows in your input increases, the performance could degrade exponentially.
library(lsa)
library(reshape2)
psm_sample <- read.csv("psm_sample.csv")
row.names(psm_sample) <-
make.names(paste0("patid.", as.character(psm_sample$subject_id)), unique = TRUE)
temp <- sapply(psm_sample, class)
temp <- cbind.data.frame(names(temp), as.character(temp))
names(temp) <- c("variable", "possible.type")
numeric.cols <- (temp$possible.type %in% c("factor", "integer") &
(!(grepl(
pattern = "_id$", x = temp$variable
))) &
(!(
grepl(pattern = "_code$", x = temp$variable)
)) &
(!(
grepl(pattern = "_type$", x = temp$variable)
))) | temp$possible.type == "numeric"
psm_numerics <- psm_sample[, numeric.cols]
row.names(psm_numerics) <- row.names(psm_sample)
psm_numerics$gender <- as.integer(psm_numerics$gender)
psm_scaled <- scale(psm_numerics)
pair.these.up <- psm_scaled
# checking for independence of variables
# if the following PDF pair plot is too big for your computer to open,
# try pair-plotting some random subset of columns
# keep.frac <- 0.5
# keep.flag <- runif(ncol(psm_scaled)) < keep.frac
# pair.these.up <- psm_scaled[, keep.flag]
# pdf device sizes are in inches
dev <-
pdf(
file = "psm_pairs.pdf",
width = 50,
height = 50,
paper = "special"
)
pairs(pair.these.up)
dev.off()
#transpose the dataframe to get the
#similarity between patients
cs <- lsa::cosine(t(psm_scaled))
# this is super inefficnet, because cs contains
# two identical triangular matrices
cs.melt <- melt(cs)
cs.melt <- as.data.frame(cs.melt)
names(cs.melt) <- c("enc.A", "enc.B", "similarity")
extract.pat <- function(enc.col) {
my.patients <-
sapply(enc.col, function(one.pat) {
temp <- (strsplit(as.character(one.pat), ".", fixed = TRUE))
return(temp[[1]][[2]])
})
return(my.patients)
}
cs.melt$pat.A <- extract.pat(cs.melt$enc.A)
cs.melt$pat.B <- extract.pat(cs.melt$enc.B)
same.pat <- cs.melt[cs.melt$pat.A == cs.melt$pat.B ,]
different.pat <- cs.melt[cs.melt$pat.A != cs.melt$pat.B ,]
most.dissimilar <-
different.pat[which.min(different.pat$similarity),]
dissimilar.pat.frame <- rbind(psm_numerics[rownames(psm_numerics) ==
as.character(most.dissimilar$enc.A) ,],
psm_numerics[rownames(psm_numerics) ==
as.character(most.dissimilar$enc.B) ,])
print(t(dissimilar.pat.frame))
which gives
patid.68.49 patid.9
gender 1.00000 2.00000
age 41.85000 41.79000
sysbp_min 72.00000 106.00000
sysbp_max 95.00000 217.00000
diasbp_min 42.00000 53.00000
diasbp_max 61.00000 107.00000
meanbp_min 52.00000 67.00000
meanbp_max 72.00000 132.00000
resprate_min 20.00000 14.00000
resprate_max 35.00000 19.00000
tempc_min 36.00000 35.50000
tempc_max 37.55555 37.88889
spo2_min 90.00000 95.00000
spo2_max 100.00000 100.00000
bicarbonate_min 22.00000 26.00000
bicarbonate_max 22.00000 30.00000
creatinine_min 2.50000 1.20000
creatinine_max 2.50000 1.40000
glucose_min 82.00000 129.00000
glucose_max 82.00000 178.00000
hematocrit_min 28.10000 37.40000
hematocrit_max 28.10000 45.20000
potassium_min 5.50000 2.80000
potassium_max 5.50000 3.00000
sodium_min 138.00000 136.00000
sodium_max 138.00000 140.00000
bun_min 28.00000 16.00000
bun_max 28.00000 17.00000
wbc_min 2.50000 7.50000
wbc_max 2.50000 13.70000
mingcs 15.00000 15.00000
gcsmotor 6.00000 5.00000
gcsverbal 5.00000 0.00000
gcseyes 4.00000 1.00000
endotrachflag 0.00000 1.00000
urineoutput 1674.00000 887.00000
vasopressor 0.00000 0.00000
vent 0.00000 1.00000
los_hospital 19.09310 4.88130
los_icu 3.53680 5.32310
sofa 3.00000 5.00000
saps 17.00000 18.00000
posthospmort30day 1.00000 0.00000
Usually I wouldn't add a second answer, but that might be the best solution here. Don't worry about voting on it.
Here's the same algorithm as in my first answer, applied to the iris data set. Each row contains four spatial measurements of the flowers form three different varieties of iris plants.
Below that you will find the iris analysis, written out as nested loops so you can see the equivalence. But that's not recommended for production with large data sets.
Please familiarize yourself with starting data and all of the intermediate dataframes:
The input iris data
psm_scaled (the spatial measurements, scaled to mean=0, SD=1)
cs (the matrix of pairwise similarities)
cs.melt (the pairwise similarities in long format)
At the end I have aggregated the mean similarities for all comparisons between one variety and another. You will see that comparisons between individuals of the same variety have mean similarities approaching 1, and comparisons between individuals of the same variety have mean similarities approaching negative 1.
library(lsa)
library(reshape2)
temp <- iris[, 1:4]
iris.names <- paste0(iris$Species, '.', rownames(iris))
psm_scaled <- scale(temp)
rownames(psm_scaled) <- iris.names
cs <- lsa::cosine(t(psm_scaled))
# this is super inefficient, because cs contains
# two identical triangular matrices
cs.melt <- melt(cs)
cs.melt <- as.data.frame(cs.melt)
names(cs.melt) <- c("enc.A", "enc.B", "similarity")
names(cs.melt) <- c("flower.A", "flower.B", "similarity")
class.A <-
strsplit(as.character(cs.melt$flower.A), '.', fixed = TRUE)
cs.melt$class.A <- sapply(class.A, function(one.split) {
return(one.split[1])
})
class.B <-
strsplit(as.character(cs.melt$flower.B), '.', fixed = TRUE)
cs.melt$class.B <- sapply(class.B, function(one.split) {
return(one.split[1])
})
cs.melt$comparison <-
paste0(cs.melt$class.A , '_vs_', cs.melt$class.B)
cs.agg <-
aggregate(cs.melt$similarity, by = list(cs.melt$comparison), mean)
print(cs.agg[order(cs.agg$x),])
which gives
# Group.1 x
# 3 setosa_vs_virginica -0.7945321
# 7 virginica_vs_setosa -0.7945321
# 2 setosa_vs_versicolor -0.4868352
# 4 versicolor_vs_setosa -0.4868352
# 6 versicolor_vs_virginica 0.3774612
# 8 virginica_vs_versicolor 0.3774612
# 5 versicolor_vs_versicolor 0.4134413
# 9 virginica_vs_virginica 0.7622797
# 1 setosa_vs_setosa 0.8698189
If you’re still not comfortable with performing lsa::cosine() on a scaled, numerical dataframe, we can certainly do explicit pairwise calculations.
The formula you gave for PSM, or cosine similarity of patients, is expressed in two formats at Wikipedia
Remembering that vectors A and B represent the ordered list of attributes for PatientA and PatientB, the PSM is the dot product of A and B, divided by (the scalar product of [the magnitude of A] and [the magnitude of B])
The terse way of saying that in R is
cosine.sim <- function(A, B) { A %*% B / sqrt(A %*% A * B %*% B) }
But we can rewrite that to look more similar to your post as
cosine.sim <- function(A, B) { A %*% B / (sqrt(A %*% A) * sqrt(B %*% B)) }
I guess you could even re-write that (the calculations of similarity between a single pair of individuals) as a bunch of nested loops, but in the case of a manageable amount of data, please don’t. R is highly optimized for operations on vectors and matrices. If you’re new to R, don’t second guess it. By the way, what happened to your millions of rows? This will certainly be less stressful now that your down to tens of thousands.
Anyway, let’s say that each individual only has two elements.
individual.1 <- c(1, 0)
individual.2 <- c(1, 1)
So you can think of individual.1 as a line that passes between the origin (0,0) and (0, 1) and individual.2 as a line that passes between the origin and (1, 1).
some.data <- rbind.data.frame(individual.1, individual.2)
names(some.data) <- c('element.i', 'element.j')
rownames(some.data) <- c('individual.1', 'individual.2')
plot(some.data, xlim = c(-0.5, 2), ylim = c(-0.5, 2))
text(
some.data,
rownames(some.data),
xlim = c(-0.5, 2),
ylim = c(-0.5, 2),
adj = c(0, 0)
)
segments(0, 0, x1 = some.data[1, 1], y1 = some.data[1, 2])
segments(0, 0, x1 = some.data[2, 1], y1 = some.data[2, 2])
So what’s the angle between vector individual.1 and vector individual.2? You guessed it, 0.785 radians, or 45 degrees.
cosine.sim <- function(A, B) { A %*% B / (sqrt(A %*% A) * sqrt(B %*% B)) }
cos.sim.result <- cosine.sim(individual.1, individual.2)
angle.radians <- acos(cos.sim.result)
angle.degrees <- angle.radians * 180 / pi
print(angle.degrees)
# [,1]
# [1,] 45
Now we can use the cosine.sim function I previously defined, in two nested loops, to explicitly calculate the pairwise similarities between each of the iris flowers. Remember, psm_scaled has already been defined as the scaled numerical values from the iris dataset.
cs.melt <- lapply(rownames(psm_scaled), function(name.A) {
inner.loop.result <-
lapply(rownames(psm_scaled), function(name.B) {
individual.A <- psm_scaled[rownames(psm_scaled) == name.A, ]
individual.B <- psm_scaled[rownames(psm_scaled) == name.B, ]
similarity <- cosine.sim(individual.A, individual.B)
return(list(name.A, name.B, similarity))
})
inner.loop.result <-
do.call(rbind.data.frame, inner.loop.result)
names(inner.loop.result) <-
c('flower.A', 'flower.B', 'similarity')
return(inner.loop.result)
})
cs.melt <- do.call(rbind.data.frame, cs.melt)
Now we repeat the calculation of cs.melt$class.A, cs.melt$class.B, and cs.melt$comparison as above, and calculate cs.agg.from.loops as the mean similarity between the various types of comparisons:
cs.agg.from.loops <-
aggregate(cs.agg.from.loops$similarity, by = list(cs.agg.from.loops $comparison), mean)
print(cs.agg.from.loops[order(cs.agg.from.loops$x),])
# Group.1 x
# 3 setosa_vs_virginica -0.7945321
# 7 virginica_vs_setosa -0.7945321
# 2 setosa_vs_versicolor -0.4868352
# 4 versicolor_vs_setosa -0.4868352
# 6 versicolor_vs_virginica 0.3774612
# 8 virginica_vs_versicolor 0.3774612
# 5 versicolor_vs_versicolor 0.4134413
# 9 virginica_vs_virginica 0.7622797
# 1 setosa_vs_setosa 0.8698189
Which, I believe is identical to the result we got with lsa::cosine.
So what I'm trying to say is... why wouldn't you use lsa::cosine?
Maybe you should be more concerned with
selection of variables, including removal of highly correlated variables
scaling/normalizing/standardizing the data
performance with a large input data set
identifying known similars and dissimilars for quality control
as previously addressed

Performing simulations and combining the data into one data frame

For each reported study, I want to do 1000 simulations of a parameter X using normal or log-normal distribution (based on a flag) and then combine all the simulations in one data frame. I am looking for an automated way of doing this.
What I have is a data frame with the following columns:
SOURCE NSUB MEAN SD DIST
Study1 10 1.5 0.3 0
Study2 5 2.5 0.4 1
Study1 4 3.5 0.3 0
when DIST==0 then it is normal distribution, if DIST==1 then it is log-normal.
I am able to do the simulations and combine them using hard coding: for example:
#for Study1:
set.seed <-1
NSUB <- 10
MEAN <- 1.5
SD <- 0.3
DIST <- 0 #Normal distribution
df1 <- data.frame("SOURCE"="Study1","NSUB"=NSUB,"DIST"=DIST, "VALUE" = rnorm(1000, mean=MEAN, sd=SD))
#For study2
set.seed <-2
NSUB <- 5
MEAN <- 2.5
SD <- 0.4
DIST <- 1 #log-normal distribution
df2 <- data.frame("SOURCE"="Study2","NSUB"=NSUB,"DIST"=DIST, "VALUE" = rlnorm(1000, meanlog=log(MEAN), sdlog=SD))
#Combine all
dfall <- rbind(df1,df2)
However, this would be tedious to me I have alot of reported means and SD for the parameter. I need help in how to make this automated so it does 1000 simulation for each row (using MEAN and SD) and then combine all simulated data in one data frame.
In the interest of implementing readable and general code, you should do two things here:
Write a function that takes each row of your simulation configuration dataset and returns the simulated values as a data_frame (doSim below). This makes it easier to test your simulation code separately from your iteration over simulation configurations.
Use dplyr to pass each row of the function to this function, and collect up the results as a data_frame.
Here is some sample code:
library(dplyr)
# read in the simultation configuration dataset
dfX = read.table(textConnection("
SOURCE NSUB MEAN SD DIST
Study1 10 1.5 0.3 0
Study2 5 2.5 0.4 1
Study1 4 3.5 0.3 0"),
header = TRUE, stringsAsFactors = FALSE)
# write a function that takes each row of the configuration
# data.frame and returns the simulations
doSim = function(simConfig, seed = 12345) {
set.seed(seed)
dist = if(simConfig[["DIST"]] == 0) rnorm else rlnorm
mean = if(simConfig[["DIST"]] == 0) simConfig[["MEAN"]] else log(simConfig[["MEAN"]])
return(
data_frame(
source = simConfig[["SOURCE"]],
nsub = simConfig[["NSUB"]],
value = dist(1000, mean = mean, sd = simConfig[["SD"]])
)
)
}
# test the function
doSim(dfX[1, ])
# apply over dfX
dfX %>%
rowwise() %>%
do(doSim(.))

Winsorize dataframe

I want to perform winsorization in a dataframe like this:
event_date beta_before beta_after
2000-05-05 1.2911707054 1.3215648954
1999-03-30 0.5089734305 0.4269575657
2000-05-05 0.5414700258 0.5326762272
2000-02-09 1.5491034852 1.2839988507
1999-03-30 1.9380674599 1.6169735009
1999-03-30 1.3109909155 1.4468207148
2000-05-05 1.2576420753 1.3659492507
1999-03-30 1.4393018341 0.7417777965
2000-05-05 0.2624037804 0.3860641307
2000-05-05 0.5532216441 0.2618245169
2000-02-08 2.6642931822 2.3815576738
2000-02-09 2.3007578964 2.2626960407
2001-08-14 3.2681270302 2.1611010935
2000-02-08 2.2509121123 2.9481325199
2000-09-20 0.6624503316 0.947935581
2006-09-26 0.6431111805 0.8745333151
By winsorization I mean to find the max and min for beta_before for example. That value should be replaced by the second highest or second lowest value in the same column, without loosing the rest of the details in the observation. For example. In this case, in beta_before the max value is 3.2681270302 and should be replaced by 3.2681270302. The same process will be followed for the min and then for the beta_after variable. Therefore, only 2 values per column will be changes, the highest and the minimum, the rest will remain the same.
Any advice? I tried different approaches in plyr, but I ended up replacing the whole observation, which I don’t want to do. I would like to create 2 new variables, for example beta_before_winsorized and beta _after_winsorized
I thought winsorizing usually finds the value x% (typically 10%, 15%, or 20%) from the bottom of the ordered list, and replaces all the values below it with that value. Same with the top. Here you're just choosing the top and bottom value, but winsorizing usually involves specifying a percentage of values at the top and bottom to replace.
Here is a function that does the winsorzation you describe:
winsorize <- function(x) {
Min <- which.min(x)
Max <- which.max(x)
ord <- order(x)
x[Min] <- x[ord][2]
x[Max] <- x[ord][length(x)-1]
x
}
If you data are in a data frame dat, then we can windsoroize the data using your procedure via:
dat2 <- dat
dat2[, -1] <- sapply(dat[,-1], winsorize)
which results in:
R> dat2
event_date beta_before beta_after
1 2000-05-05 1.2911707 1.3215649
2 1999-03-30 0.5089734 0.4269576
3 2000-05-05 0.5414700 0.5326762
4 2000-02-09 1.5491035 1.2839989
5 1999-03-30 1.9380675 1.6169735
6 1999-03-30 1.3109909 1.4468207
7 2000-05-05 1.2576421 1.3659493
8 1999-03-30 1.4393018 0.7417778
9 2000-05-05 0.5089734 0.3860641
10 2000-05-05 0.5532216 0.3860641
11 2000-02-08 2.6642932 2.3815577
12 2000-02-09 2.3007579 2.2626960
13 2001-08-14 2.6642932 2.1611011
14 2000-02-08 2.2509121 2.3815577
15 2000-09-20 0.6624503 0.9479356
16 2006-09-26 0.6431112 0.8745333
I'm not sure where you got the value you suggest should replace the max in beta_before as the second highest is 2.6642932 in the snippet of data provided and that is what my function has used to replace with the maximum value with.
Note the function will only work if there is one minimum and maximum values respectively in each column owing to the way which.min() and which.max() are documented to work. If you have multiple entries taking the same max or min value then we would need something different:
winsorize2 <- function(x) {
Min <- which(x == min(x))
Max <- which(x == max(x))
ord <- order(x)
x[Min] <- x[ord][length(Min)+1]
x[Max] <- x[ord][length(x)-length(Max)]
x
}
should do it (latter is not tested).
Strictly speaking, "winsorization" is the act of replacing the most extreme data points with an acceptable percentile (as mentioned in some of the other answers). One fairly standard R function to do this is winsor from the psych package. Try:
dat$beta_before = psych::winsor(dat$beta_before, trim = 0.0625)
dat$beta_after = psych::winsor(dat$beta_after , trim = 0.0625)
I chose trim = to be 0.0625 (the 6.25th percentile and 93.75th percentile) because you only have 16 data points and you want to "rein in" the top and bottom ones: 1/16 = 0.0625
Note that this might make the extreme data equal to a percentile number which may or may not exist in your data set: the theoretical n-th percentile of the data.
The statar package works very well for this. Copying the relevant snippet from the readme file:
# winsorize (default based on 5 x interquartile range)
v <- c(1:4, 99)
winsorize(v)
winsorize(v, replace = NA)
winsorize(v, probs = c(0.01, 0.99))
winsorize(v, cutpoints = c(1, 50))
https://github.com/matthieugomez/statar
follow up from my previous point about actually replacing the to-be-trimmed values with value at trim position:
winsorized.sample<-function (x, trim = 0, na.rm = FALSE, ...)
{
if (!is.numeric(x) && !is.complex(x) && !is.logical(x)) {
warning("argument is not numeric or logical: returning NA")
return(NA_real_)
}
if (na.rm)
x <- x[!is.na(x)]
if (!is.numeric(trim) || length(trim) != 1L)
stop("'trim' must be numeric of length one")
n <- length(x)
if (trim > 0 && n) {
if (is.complex(x))
stop("trimmed sample is not defined for complex data")
if (any(is.na(x)))
return(NA_real_)
if (trim >= 0.5) {
warning("trim >= 0.5 is odd...trying it anyway")
}
lo <- floor(n * trim) + 1
hi <- n + 1 - lo
#this line would work for just trimming
# x <- sort.int(x, partial = unique(c(lo, hi)))[lo:hi]
#instead, we're going to replace what would be trimmed
#with value at trim position using the next 7 lines
idx<-seq(1,n)
myframe<-data.frame(idx,x)
myframe<-myframe[ order(x,idx),]
myframe$x[1:lo]<-x[lo]
myframe$x[hi:n]<-x[hi]
myframe<-myframe[ order(idx,x),]
x<-myframe$x
}
x
}
#test it
mydist<-c(1,20,1,5,2,40,5,2,6,1,5)
mydist2<-winsorized.sample(mydist, trim=.2)
mydist
mydist2
descStat(mydist)
descStat(mydist2)

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