Using multiple UpdatePanels on a single page without interfering with each other - asp.net

Question

It seems that when multiple UpdatePanels are on a single page, anytime an asyncPostBack occurs on one, all others will have their html reloaded. Is there a way around this?
Example
Example.aspx
<asp:UpdatePanel ID="UpdatePanel1" runat="server">
<ContentTemplate>
<div style="border: 1px solid black;">
<asp:TextBox runat="server" ID="txtTEST1" />
<asp:Label runat="server" ID="lblTEST1" />
<asp:Button runat="server" ID="btnTEST1" Text="AsyncPostBack1" />
<div onclick="this.innerHTML='Wooo!'">Click Me - UpdatePanel1</div>
</div>
</ContentTemplate>
</asp:UpdatePanel>
<div onclick="this.innerHTML='Wooo!'" style="padding: 1em;">Click Me. I'm not part of an Update Panel</div>
<asp:UpdatePanel ID="UpdatePanel2" runat="server">
<ContentTemplate>
<div style="border: 1px solid black;">
<asp:TextBox runat="server" ID="TextBox1" />
<asp:Label runat="server" ID="Label1" />
<asp:Button runat="server" ID="Button1" Text="AsyncPostBack2" />
<div onclick="this.innerHTML='Wooo!'">Click Me - UpdatePanel2</div>
</div>
</ContentTemplate>
</asp:UpdatePanel>
Example.aspx.vb
Protected Sub btnTEST1_Click(sender As Object, e As EventArgs) Handles btnTEST1.Click
lblTEST1.Text = "Refreshed at " & DateTime.Now.ToString()
End Sub
Protected Sub Button1_Click(sender As Object, e As EventArgs) Handles Button1.Click
Label1.Text = "Refreshed at " & DateTime.Now.ToString()
End Sub
Testing the issue
Click on all 3 of the divs with the "Click Me" text so that HTML is altered inside and outside of the UpdatePanels.
Click one of the buttons labeled "AsyncPostBack". Regardless on which one is clicked, both UpdatePanels will have their HTML rerendered and replaced, as seen by the 2 divs inside the UpdatePanels resetting to their original text.
So I ask, is it possible to have multiple UpdatePanels on the same page that don't cause each other to rerender every time one of them has a asyncPostBack event.

Answer 1

yes
set updatemode=conditional
provide the triggers which will trigger the update. here is a link to an example. (#1 result on google) http://ajax.net-tutorials.com/controls/updatepanel-control/

Answer 2

Try adding mode to update panel tag. If mode is not give the default mode is always. If the UpdateMode property is Always, the UpdatePanel control's content is updated on every postback that originates from anywhere on the page. Microsoft documentation about UpdateMode
<asp:UpdatePanel ID="BugsListUpdatePanel" runat="server" UpdateMode="Conditional">